
Paroxysmal Nocturnal Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria is a rare blood disease that destroys red blood cells, impairs blood marrow function, and increases the risk of thrombosis (blood clots). It’s the result of a mutation of a gene called PIG-A, which is located in the stem cells of bone marrow. The affected stem cells pass on the mutation to all cells that derive from it. The condition is life-threatening and can develop at any age.
The symptoms of paroxysmal nocturnal hemoglobinuria can range from person to person. Some experience all of them, while others only notice a few of the signs. The most common ones include:
Severe headaches
Irregular heartbeat
Fatigue
Shortness of breath
Flu-like symptoms
Difficulties swallowing
Difficulties controlling bleeding
Bruising easily
Abdominal pain
Recurring infections
Chronic back pain
Bright red blood in the urine
Blood in the urine can also show up looking darker. It is also common for it to be very noticeable in the morning, while clearing up throughout the day. It may also be more noticeable if you’re experiencing an infection, taking certain medications, or undergoing a lot of stress.
Treatments perscribed by:
Referral Forms
Click on the link below to see all refferal forms or select a associated treatment below in Associated Treatements to view detail and download the relative treatment refferal form.
All Referral Forms