Lupus Nephritis

Understanding Lupus Nephritis

Lupus Nephritis is a serious kidney complication of Systemic Lupus Erythematosus (SLE), where the immune system mistakenly attacks the kidneys, causing inflammation and damage. Over time, this can lead to progressive kidney failure if left untreated. Lupus Nephritis is classified into six stages (I-VI) based on severity, with Class III-V (focal, diffuse, and membranous nephritis) often requiring more aggressive treatment.

Common Signs and Symptoms of Lupus Nephritis:

• Urinary Changes: Blood or protein in the urine, which may cause the urine to appear foamy or dark.
• Swelling: Edema, particularly in the legs, ankles, or around the eyes, due to fluid retention.
• High Blood Pressure: Elevated blood pressure that can further stress the kidneys.
• Fatigue: Persistent tiredness or general malaise.
• Flank Pain: Discomfort or pain in the lower back or sides where the kidneys are located.
• Weight Gain: Sudden, unexplained weight gain, often related to fluid retention.

This information is provided as a resource and is not intended to diagnose a condition or prescribe treatment. Please discuss any symptoms you may exhibit with your physician.