Chronic Inflammatory Demyelinating Polyneuropathy

Understanding Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare autoimmune neurological disorder in which the immune system attacks the myelin sheath—the protective covering of nerves. This damage results in progressive weakness, numbness, and a loss of reflexes in the arms and legs. Often considered the chronic counterpart of Guillain-Barré Syndrome (GBS), CIDP develops gradually over weeks to months rather than occurring suddenly. If left untreated, CIDP can lead to permanent nerve damage, although many patients respond well to immune-modulating therapies.

Common Signs and Symptoms of CIDP:

• Progressive Muscle Weakness: Gradual loss of strength in the arms and legs, which may worsen with activity.
• Sensory Changes: Numbness, tingling, or a “pins and needles” sensation in the affected limbs.
• Loss of Reflexes: Reduced or absent reflex responses, particularly in the knees and ankles.
• Fatigue and Discomfort: Persistent tiredness and muscle aches, impacting daily activities.
• Impaired Coordination: Difficulty with balance and fine motor skills due to nerve damage.

This information is provided as a resource and is not intended to diagnose a condition or prescribe treatment. Please discuss any symptoms you may exhibit with your physician.