Skyrizi

Skyrizi®

Understanding Skyrizi® (risankizumab-rzaa)

Skyrizi® (risankizumab-rzaa) is a targeted biologic therapy used to treat autoimmune diseases by blocking interleukin-23 (IL-23), a key protein that drives inflammation. By inhibiting IL-23, Skyrizi® helps reduce inflammatory responses, alleviating symptoms such as skin plaques, joint pain, and digestive issues associated with various autoimmune conditions.

How Skyrizi® Works:

  • Blocks IL-23, a cytokine involved in autoimmune inflammation
  • Reduces inflammatory responses, improving skin, joint, and digestive symptoms
  • Helps manage chronic autoimmune diseases, offering long-term symptom relief

FDA Approvals:

  • Moderate to Severe Plaque Psoriasis: Approved on April 23, 2019
  • Psoriatic Arthritis (PsA): Expanded approval on January 21, 2022
  • Crohn’s Disease (CD): Expanded approval on June 17, 2022

For more information, please visit the Skyrizi® patient website and speak with your healthcare provider to determine if Skyrizi® is the right treatment option for you.

Referral Form:
MANUFACTURER:

AbbVie Inc.

CLASS:
Interleukin-23 (IL-23) Inhibitor
HOW ADMINISTERED:
For Plaque Psoriasis & Psoriatic Arthritis Subcutaneous Injection For Crohn’s Disease (IV Infusion + Subcutaneous Injection)
FREQUENCY:

For Plaque Psoriasis & Psoriatic Arthritis First two doses: At Week zero and Week four, then every twelve weeks.
For Crohn’s Disease Given as a single IV infusion, then Subcutaneous Injection every eight weeks.

Length of infusion:
About 60 mins

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