Yesintek®

Understanding Yesintek™
Yesintek™ (satralizumab-mwge) is a monoclonal antibody developed to treat neuromyelitis optica spectrum disorder (NMOSD) in adults who are anti-AQP4 antibody positive. It works by blocking interleukin-6 (IL-6) receptors, a key signaling pathway in the inflammatory process associated with NMOSD. By targeting IL-6, Yesintek™ helps reduce the risk of relapses that can lead to serious, lasting neurological damage.

How Yesintek™ Works:

  • Inhibits IL-6 receptors to limit immune-driven inflammation in the central nervous system
  • Helps prevent relapses of NMOSD, which may cause vision impairment, paralysis, or mobility issues
  • Aims to preserve neurological function by reducing disease activity over time
  • Can be used as a standalone treatment or alongside other immunosuppressants, depending on clinical recommendations

FDA Approval:
2020 – Approved for the treatment of anti-AQP4 antibody-positive NMOSD in adult patients.

For more information, speak with your healthcare provider or visit the official Yesintek™ patient website to learn if Yesintek™ is appropriate for your treatment plan.

Referral Form:
MANUFACTURER:

Sandoz Inc.

CLASS:
Monoclonal Antibody (mAb) Interleukin Inhibitor - Specifically: IL-12 and IL-23 antagonist
HOW ADMINISTERED:
Subcutaneous Injection
FREQUENCY:

Initially once every 2 weeks for the first 3 doses. Then, once injection every 4 weeks.

Length of infusion:
About 30 mins
FOR MORE INFORMATION:

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